When the doctor told me I had Ureterolithiasis, I logged into 23andme to check my genetic risk. There was only one SNP (rs4293393) listed there. The G allele increased the risk 14% but I have AA, so typical odds. Next step was checking SNPedia where I found 8 SNPs, of which some are given below.… Continue reading Genetics and Health
Author: Zack
Dad, gadget guy, bookworm, political animal, global nomad, cyclist, hiker, tennis player, photographer
Punjabi and What?
Looking at the admixture analysis for my Harappa Ancestry Project, I count 6 Punjabis (not including my sister and I). Let’s average those six and compare them to me and my sister. Ancestral Pop Average Punjabi Me My sister NSA1 NSA2 South Asian 46% 38% 35% 7% 7% Balochistan/Caucasus 35% 35% 34% 32% 30% Kalash… Continue reading Punjabi and What?
Harappa Clustering
As I had computed the admixture percentages for myself, my sister and other participants in my Harappa Ancestry Project, I decided to do some clustering analysis on them to see which persons clustered together. The resulting tree for a hierarchical clustering is as follows. It shows which persons are the most similar. I am HRP0001… Continue reading Harappa Clustering
My Harappa Project Results
I have been blogging up a storm on Harappa Ancestry Project with more than 50 posts since I last linked to it. Let’s see what I have found out about myself there. Here are the admixture results for me and my sister: Me My sister South Asian 37.9% 34.8% Balochistan/Caucasus 34.7% 34.2% Southwest Asian 9.8%… Continue reading My Harappa Project Results
Your Genes, Regulated?
The FDA had a meeting the last two days: FDA is convening this two-day meeting to seek the Panel’s expert opinion and input on scientific issues concerning Direct to Consumer (DTC) genetic tests that make medical claims. This meeting is focused specifically on issues regarding clinical genetic tests that are marketed directly to consumers (DTC… Continue reading Your Genes, Regulated?
Eurogenes
Davidski of Eurogenes is also a genome blogger. In his admixture analysis for West, South and Central Asians, I am PKEG1 and my results are as follows: European 4% Siberian 1% Caucasus 32% Sub-Saharan African 4% Middle Eastern 9% East Asian 1% South Asian 50% Here’s a chart showing some of the reference samples and… Continue reading Eurogenes
Dodecad Project II
I talked about the Dodecad Project last time. Dienekes also did some cluster analysis using mclust. When he classified everybody into 48 clusters, I showed up almost all alone in cluster 21. Only one other member who is a Bihari Brahmin had a 50% chance of belonging in my cluster. With 56 clusters, I am… Continue reading Dodecad Project II
Dodecad Ancestry Project
I asked Dienekes to include me in his Dodecad Ancestry Project and he gave me the following results: Ancestral Component Percentage South Asian 44.9% West Asian 33.7% Southwest Asian 5.7% North European 5.5% South European 3.7% East African 3.4% Northwest African 2.1% West African 0.6% East Asian 0.4% Northeast Asian 0.1% You can see the… Continue reading Dodecad Ancestry Project
McDonald Ancestry Analysis II
When my sister got her 23andme results, we sent them over to Doug McDonald. I was expecting something close to my results, but it was radically different: This one is different it says 37% Druze, 4% Bushman or Pygmy, the rest North India. It is complicated enough that the program refuses to generate a spot… Continue reading McDonald Ancestry Analysis II
Doug McDonald Ancestry Analysis
As I noted last time, I was in a situation where I needed some help into ascertaining my genetic ancestry. Fortunately, there are people willing to do that sort of analysis for you. One of these is Doug McDonald. So I sent him my data and within an hour I had an analysis. The PCA… Continue reading Doug McDonald Ancestry Analysis